Intracellular Motility: Myosin and Tropomyosin in Actin Cable Flow
نویسنده
چکیده
A new study has found that retrograde flow of budding yeast actin cables is facilitated by myosin II but is inhibited by a specific tropomyosin isoform (Tpm2p). Budding yeast therefore contains a minimal component system for elucidating the mechanistic details of retrograde actin flow.
منابع مشابه
Roles of type II myosin and a tropomyosin isoform in retrograde actin flow in budding yeast
Retrograde flow of cortical actin networks and bundles is essential for cell motility and retrograde intracellular movement, and for the formation and maintenance of microvilli, stereocilia, and filopodia. Actin cables, which are F-actin bundles that serve as tracks for anterograde and retrograde cargo movement in budding yeast, undergo retrograde flow that is driven, in part, by actin polymeri...
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عنوان ژورنال:
- Current Biology
دوره 17 شماره
صفحات -
تاریخ انتشار 2007